An Introduction to the Theory of Observational Studies

This book is an introduction to the theory of causal inference in observational studies. An observational study draws inferences about the effects caused by treatments or preventable exposures when randomized experimentation is unethical or infeasible. An observational study is distinguished from an experiment by the problems that follow from the absence of randomized assignment of individuals to treatments. Observational studies are common in most fields that study the effects of treatments or policies on people, including public health and epidemiology, economics and public policy, medicine and clinical psychology, and criminology and empirical legal studies. After Part I reviews causal inference in randomized experiments, the twelve short chapters in Parts II, III and IV introduce modern topics: the propensity score, ignorable treatment assignment, the principal unobserved covariate, algorithms for optimal matching, randomized reassignment techniques for appraising the